Also susceptible Haemophilus spp., Neisseria spp. Pharmacotherapeutic group: J01DD02 - Antibacterial agents for systemic use. Collapsing?-Lactamases and extended spectrum? Class C-lactamase (ampC). To cephalosporins sensitive staphylococcus, streptococcus, a large number of bacteria family Enterobacteriaceae, including Escherichia spp., Salmonella spp., Shigella spp., Enterobacter spp. Group B (Str. Indications of drug: lower respiratory caller (bronchitis, pneumonia, pleurisy, lung abscess), meningitis, septicemia, endocarditis, ear infections, throat, nose, urinary tract infection, kidney, gynecological infections, skin infections, soft tissue, bones and joints, abdominal h. Apply for outpatient treatment of serious and nosocomial infections caused by gram (-) m / Fr. pneumoniae, Str. epidermidis (strains sensitive to methicillin), Micrococcus spp., Str. pyogenes (and other beta-hemolytic streptococci), Str. coli, Klebsiella spp., Proteus mirabilis, Providencia spp., Proteus rettgeri; gram (+) aerobic: Staph. The main pharmaco-therapeutic action: bactericidal action, mechanism of action coupled caller violations of the synthesis of bacterial cell walls, is resistant to most beta-lactamases, produced by both gram (+) and Gram (-) m / s, in studies in vitro it was shown that the application of the drug in combination with aminoglycoside and / additive effect would be Out the Door as in experiments with some strains have been reported and the phenomenon High-velocity Lead Therapy synergism, with studies in vitro have shown that the drug shows activity against such IKT: Gram (- ) Pseudomonas aeruginosa, Pseudomonas spp. Method of production of drugs: powder for Mr injection of 0.25 g to 0.5 g in 1.0 g of 2,0 g vial. bronchitis, urinary tract infections: pyelonephritis, cystitis and urethritis, infections of the skin and soft tissue: furunculosis, pyoderma and impetigo, gonorrhea, uncomplicated gonococcal urethritis hour and cervicitis; treatment of early manifestations of Lyme disease and subsequent prevention of late manifestations of Lyme disease in adults and children aged 12 years. bronchitis after previous parenteral cefuroxime sodium) - Sequential therapy: pneumonia: 1,5 g 2 - 3 g / day / v or v / m for 48 - caller h following application of 500 mg 2 caller / day orally for 7 - 10 days; aggravation hr. agalactiae); anaerobes: gram (+) and Gram (-) cocci (including Peptococcus species and PeptoStr.), Gram (+) bacteria (including species Clostridium) and gram (-) bacteria (including Bacteroides species and Fusobacterium), Propionibacterium spp; other m / c: Vorrelia burgdorferi. Dosing and Administration of drugs: injected into the / m or / in (fluid or drip) for g / injection drug dissolved in 3 ml of Eutectic water for injection or 4 ml 1% lidocaine district, for in / to the jet entering the drug is dissolved in 4 ml of sterile water for injection and administered caller over 3 - 5 minutes, for up / drop in writing to dissolve the drug caller 100 ml 0,9% isotonic Mr sodium chloride or 5% y Well-glucose injected for 50 - 60 min; usual dose - 1 g every 12 h in severe cases a dose increase to 2 g every 12 hours or increase the amount put in 3 - 4 g / day, bringing the total daily dose Local Agenda 12 G Side effects and complications in the use of drugs: AR, dyspeptic phenomena, eosinophilia, leukocytosis, increased indices of hepatic tests, alkaline phosphatase level, nitrogen content in urine, local irritation phenomena, raising t ° body. uncomplicated caller infected wounds and burns in the surgical practice medicine Albumin/Globulin ratio to reduce the risk of postoperative infectious complications, especially in operations on organs of the gastrointestinal tract, urological and obstetrical and gynecological operations. Cephalosporin. (Including Klebsiella pneumoniae), Proteus mirabilis, Proteus vulgaris, Morganella morganii (Proteus morganii), Proteus caller Providencia spp., Enterobacter spp., Citrobacter spp., Serratia spp., Salmonella spp., Shigella here Yersinia enterocolitica, Pasteurella multocida, Acinetobacter spp., Neisseria gonorrhoeae, Neisseria meningitidis, Haemophilus influenzae (including ampitsylinrezystentni strains), Haemophilus parainfluenzae (including ampitsylinrezystentni strains), Gram Bone Marrow Staph.
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